This article explores how challenges such as sequence optimization, immune activation and off-target effects are being ...

From enzymes and lipid nanoparticles to large-scale process design, four global innovators redefine RNA-based medicine development and delivery.

A new class of lipids improve the rates at which lipid nanoparticles (LNPs) successfully deliver RNA therapeutics and gene editing tools, promising to increase their effectiveness of such treatments.

At a virtual conference in November 2020, the winner of a biennial protein-structure-prediction challenge was announced: AlphaFold. Created by Google DeepMind, this computational tool had blown its ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...